Optimizing amino acid substitution matrices with a local alignment kernel
<p>Abstract</p> <p>Background</p> <p>Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, called a <it>local alignment kernel</it>, that exhibits g...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2006-05-01
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| Series: | BMC Bioinformatics |
| Online Access: | http://www.biomedcentral.com/1471-2105/7/246 |