GABAA receptors: structure, function, pharmacology, and related disorders

GABAA receptors: structure, function, pharmacology, and related disorders

Abstract Background γ-Aminobutyric acid sub-type A receptors (GABAARs) are the most prominent inhibitory neurotransmitter receptors in the CNS. They are a family of ligand-gated ion channel with significant physiological and therapeutic implications. Main body GABAARs are heteropentamers formed from...

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Bibliographic Details
Main Authors: Amr Ghit, Dina Assal, Ahmed S. Al-Shami, Diaa Eldin E. Hussein
Format: Article
Language:English
Published: SpringerOpen 2021-08-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
GABA
GABAAR
Benzodiazepine
Barbiturates
Allosteric modulation
Autism spectrum disorder
Online Access:https://doi.org/10.1186/s43141-021-00224-0

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