An Introspective Approach: A Lifetime of Parkinson’s Disease Research and Not Much to Show for it Yet?
I feel part of a massive effort to understand what is wrong with motor systems in the brain relating to Parkinson’s disease. Today, the symptoms of the disease can be modified slightly, but dopamine neurons still die; the disease progression continues inexorably. Maybe the next research phase will b...
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MDPI AG
2021-02-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/10/3/513 |
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doaj-5de6973002e94539b30584e4deca46442021-03-01T00:01:49ZengMDPI AGCells2073-44092021-02-011051351310.3390/cells10030513An Introspective Approach: A Lifetime of Parkinson’s Disease Research and Not Much to Show for it Yet?Gordon W. Arbuthnott0Brain Mechanisms for Behaviour Unit, Okinawa Institute of Science and Technology, Graduate University, Onna-son, Okinawa 904-0495, JapanI feel part of a massive effort to understand what is wrong with motor systems in the brain relating to Parkinson’s disease. Today, the symptoms of the disease can be modified slightly, but dopamine neurons still die; the disease progression continues inexorably. Maybe the next research phase will bring the power of modern genetics to bear on halting, or better, preventing cell death. The arrival of accessible human neuron assemblies in organoids perhaps will provide a better access to the processes underlying neuronal demise.https://www.mdpi.com/2073-4409/10/3/513Parkinson’s diseasealpha-synucleingeneticsdeep brain stimulationorganoidsanatomy |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Gordon W. Arbuthnott |
| spellingShingle |
Gordon W. Arbuthnott An Introspective Approach: A Lifetime of Parkinson’s Disease Research and Not Much to Show for it Yet? Cells Parkinson’s disease alpha-synuclein genetics deep brain stimulation organoids anatomy |
| author_facet |
Gordon W. Arbuthnott |
| author_sort |
Gordon W. Arbuthnott |
| title |
An Introspective Approach: A Lifetime of Parkinson’s Disease Research and Not Much to Show for it Yet? |
| title_short |
An Introspective Approach: A Lifetime of Parkinson’s Disease Research and Not Much to Show for it Yet? |
| title_full |
An Introspective Approach: A Lifetime of Parkinson’s Disease Research and Not Much to Show for it Yet? |
| title_fullStr |
An Introspective Approach: A Lifetime of Parkinson’s Disease Research and Not Much to Show for it Yet? |
| title_full_unstemmed |
An Introspective Approach: A Lifetime of Parkinson’s Disease Research and Not Much to Show for it Yet? |
| title_sort |
introspective approach: a lifetime of parkinson’s disease research and not much to show for it yet? |
| publisher |
MDPI AG |
| series |
Cells |
| issn |
2073-4409 |
| publishDate |
2021-02-01 |
| description |
I feel part of a massive effort to understand what is wrong with motor systems in the brain relating to Parkinson’s disease. Today, the symptoms of the disease can be modified slightly, but dopamine neurons still die; the disease progression continues inexorably. Maybe the next research phase will bring the power of modern genetics to bear on halting, or better, preventing cell death. The arrival of accessible human neuron assemblies in organoids perhaps will provide a better access to the processes underlying neuronal demise. |
| topic |
Parkinson’s disease alpha-synuclein genetics deep brain stimulation organoids anatomy |
| url |
https://www.mdpi.com/2073-4409/10/3/513 |
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