Clostridium butyricum CGMCC0313.1 Protects against Autoimmune Diabetes by Modulating Intestinal Immune Homeostasis and Inducing Pancreatic Regulatory T Cells

Clostridium butyricum CGMCC0313.1 Protects against Autoimmune Diabetes by Modulating Intestinal Immune Homeostasis and Inducing Pancreatic Regulatory T Cells

Recent evidence indicates that indigenous Clostridium species induce colonic regulatory T cells (Tregs), and gut lymphocytes are able to migrate to pancreatic islets in an inflammatory environment. Thus, we speculate that supplementation with the well-characterized probiotics Clostridium butyricum C...

Full description

Bibliographic Details
Main Authors:	Lingling Jia, Kai Shan, Li-Long Pan, Ninghan Feng, Zhuwu Lv, Yajun Sun, Jiahong Li, Chengfei Wu, Hao Zhang, Wei Chen, Julien Diana, Jia Sun, Yong Q. Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-10-01
Series:	Frontiers in Immunology
Subjects:	type 1 diabetes butyrate-producing bacteria regulatory T cells gut microbiota regulatory T cells migration
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01345/full

Similar Items

Anti-diabetic Effects of Clostridium butyricum CGMCC0313.1 through Promoting the Growth of Gut Butyrate-producing Bacteria in Type 2 Diabetic Mice
by: Lingling Jia, et al.
Published: (2017-08-01)

Clostridium Butyricum CGMCC0313.1 Modulates Lipid Profile, Insulin Resistance and Colon Homeostasis in Obese Mice.
by: Haixiao Shang, et al.
Published: (2016-01-01)

Corrigendum: Inulin-Type Fructans Modulates Pancreatic-Gut Innate Immune Responses and Gut Barrier Integrity during Experimental Acute Pancreatitis in a Chain Length-Dependent Manner
by: Yue He, et al.
Published: (2018-04-01)

Inulin-Type Fructans Modulates Pancreatic–Gut Innate Immune Responses and Gut Barrier Integrity during Experimental Acute Pancreatitis in a Chain Length-Dependent Manner
by: Yue He, et al.
Published: (2017-09-01)

Role of Regulatory T Cells in Disturbed Immune Homeostasis in Patients With Chronic Obstructive Pulmonary Disease
by: Jia Hou, et al.
Published: (2020-04-01)

Correlation of peripheral blood mir-146b and mir-155 expression with Treg immunity and myocardial injury in children with viral myocarditis
by: Yuan Long, et al.
Published: (2017-11-01)

Alterations of Gut Microbiota and Blood Lipidome in Gestational Diabetes Mellitus With Hyperlipidemia
by: He Liu, et al.
Published: (2019-08-01)

CeRNA Expression Profiling Identifies KIT-Related circRNA-miRNA-mRNA Networks in Gastrointestinal Stromal Tumour
by: Ning Jia, et al.
Published: (2019-09-01)

An integrative multi-omics network-based approach identifies key regulators for breast cancer
by: Yi-Xiao Chen, et al.
Published: (2020-01-01)

The Role of Glyceraldehyde-3-Phosphate Dehydrogenases in NADPH Supply in the Oleaginous Filamentous Fungus Mortierella alpina
by: Shunxian Wang, et al.
Published: (2020-04-01)

Combinatory antibiotic treatment protects against experimental acute pancreatitis by suppressing gut bacterial translocation to pancreas and inhibiting NLRP3 inflammasome pathway
by: Lingling Jia, et al.
Published: (2020-01-01)

Perioperative dynamic alterations in peripheral regulatory T and B cells in patients with hepatocellular carcinoma
by: Chen Tianxiang, et al.
Published: (2012-01-01)

Programmed death-1 expression and regulatory T cells increase in the Intestinal mucosa of cytomegalovirus colitis in patients with HIV/AIDS
by: Lei Sun, et al.
Published: (2020-09-01)

Sulforaphane Protects Pancreatic Acinar Cell Injury by Modulating Nrf2-Mediated Oxidative Stress and NLRP3 Inflammatory Pathway
by: Zhaojun Dong, et al.
Published: (2016-01-01)

Transcriptome and Resequencing Analyses Provide Insight into Differences in Organic Acid Accumulation in Two Pear Varieties
by: Qionghou Li, et al.
Published: (2021-09-01)

調節焦點契合之後設分析
by: 陳玉珊, et al.

TIGIT enhances CD4+ regulatory T‐cell response and mediates immune suppression in a murine ovarian cancer model
by: Fengzhen Chen, et al.
Published: (2020-05-01)

Neurexin–Neuroligin 1 regulates synaptic morphology and functions via the WAVE regulatory complex in Drosophila neuromuscular junction
by: Guanglin Xing, et al.
Published: (2018-03-01)

Modulation of Gut Microbiota by Low Methoxyl Pectin Attenuates Type 1 Diabetes in Non-obese Diabetic Mice
by: Chengfei Wu, et al.
Published: (2019-07-01)

Corrigendum: Recent Advances on Nutrition in Treatment of Acute Pancreatitis
by: Li-Long Pan, et al.
Published: (2018-04-01)

Recent Advances on Nutrition in Treatment of Acute Pancreatitis
by: Li-Long Pan, et al.
Published: (2017-06-01)

Lactose Induces Phenotypic and Functional Changes of Neutrophils and Macrophages to Alleviate Acute Pancreatitis in Mice
by: Li-Long Pan, et al.
Published: (2018-04-01)

Recombinant CRAMP-producing Lactococcus lactis attenuates dextran sulfate sodium-induced colitis by colonic colonization and inhibiting p38/NF-κB signaling
by: Jiahong Li, et al.
Published: (2021-09-01)

Tripterygium wilfordii Polyglycoside Ameliorated TNBS-Induced Colitis in Rats via Regulating Th17/Treg Balance in Intestinal Mucosa
by: Zhang C, et al.
Published: (2021-04-01)

Promoting Water Conservation Based on the Matching Effect of Regulatory Focus and Emotion
by: Xiaomei Wang, et al.
Published: (2021-02-01)

Estradiol Attenuates the Severity of Primary Toxoplasma gondii Infection-Induced Adverse Pregnancy Outcomes Through the Regulation of Tregs in a Dose-Dependent Manner
by: Jingfan Qiu, et al.
Published: (2018-05-01)

Hypothermia Protects Mice Against Ischemic Stroke by Modulating Macrophage Polarization Through Upregulation of Interferon Regulatory Factor-4
by: Yu X, et al.
Published: (2021-04-01)

Ketamine exerts a protective role in a cell-based model of major depressive disorder via the inhibition of apoptosis and inflammation and activation of the Krebs cycle
by: Wenfei Zhang, et al.
Published: (2019-06-01)

SOCS3 Negatively Regulates Cardiac Hypertrophy via Targeting GRP78-Mediated ER Stress During Pressure Overload
by: Shuang Liu, et al.
Published: (2021-01-01)

Identification of potential crucial genes and construction of microRNA-mRNA negative regulatory networks in osteosarcoma
by: Yue Pan, et al.
Published: (2018-05-01)

Imbalance between subsets of CD8+ peripheral blood T cells in patients with chronic obstructive pulmonary disease
by: Long Chen, et al.
Published: (2016-08-01)

Overview on current criteria for heavy metals and its hint for the revision of soil environmental quality standards in China
by: Shi-bao CHEN, et al.
Published: (2018-04-01)

OsPRR37 Alternatively Promotes Heading Date Through Suppressing the Expression of Ghd7 in the Japonica Variety Zhonghua 11 under Natural Long-Day Conditions
by: Yong Hu, et al.
Published: (2021-02-01)

Thermal-hydraulic Performance Analysis of Corrugated Plate Heat Exchanger
by: Wei Q. Tan, et al.
Published: (2018-08-01)

Human Mesenchymal Stem Cells Elevate CD4+CD25+CD127low/- Regulatory T Cells of Asthmatic Patients via Heme Oxygenase-1
by: Jian-guo Li, et al.
Published: (2013-09-01)

Tumor-Derived Extracellular Vesicles: Their Role in Immune Cells and Immunotherapy
by: Li Q, et al.
Published: (2021-08-01)

Regulatory Networks of LncRNA MALAT-1 in Cancer
by: Fu S, et al.
Published: (2020-10-01)

The mixture of corn and wheat peptide prevent diabetes in NOD mice
by: Suling Sun, et al.
Published: (2019-05-01)

Reducing Lung ATP Levels and Alleviating Asthmatic Airway Inflammation through Adeno-Associated Viral Vector-Mediated CD39 Expression
by: Yung-An Huang, et al.
Published: (2021-06-01)

Tetrahydrobiopterin Plays a Functionally Significant Role in Lipogenesis in the Oleaginous Fungus Mortierella alpina
by: Hongchao Wang, et al.
Published: (2020-02-01)

Cannot write session to /tmp/vufind_sessions/sess_ogsulmb2nmde2f7tf6f6ud39rf