<i>Babesia divergens</i>: A Drive to Survive

<i>Babesia divergens</i>: A Drive to Survive

<i>Babesia divergens</i> is an obligate intracellular protozoan parasite that causes zoonotic disease. Central to its pathogenesis is the ability of the parasite to invade host red blood cells of diverse species, and, once in the host blood stream, to manipulate the composition of its po...

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Main Authors: Cheryl A Lobo, Jeny R Cursino-Santos, Manpreet Singh, Marilis Rodriguez
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Pathogens
Subjects:
Babesia
invasion
malaria
persistence
population structure
Online Access:https://www.mdpi.com/2076-0817/8/3/95
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spelling doaj-5ddac81f528e4deaaff85be1cc712ad92020-11-25T01:33:25ZengMDPI AGPathogens2076-08172019-07-01839510.3390/pathogens8030095pathogens8030095<i>Babesia divergens</i>: A Drive to SurviveCheryl A Lobo0Jeny R Cursino-Santos1Manpreet Singh2Marilis Rodriguez3Department of Blood Borne Parasites, Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 100065, USADepartment of Blood Borne Parasites, Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 100065, USADepartment of Blood Borne Parasites, Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 100065, USADepartment of Blood Borne Parasites, Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 100065, USA<i>Babesia divergens</i> is an obligate intracellular protozoan parasite that causes zoonotic disease. Central to its pathogenesis is the ability of the parasite to invade host red blood cells of diverse species, and, once in the host blood stream, to manipulate the composition of its population to allow it to endure unfavorable conditions. Here we will review key in vitro studies relating to the survival strategies that <i>B. divergens</i> adopts during its intraerythrocytic development to persist and how proliferation is restored in the parasite population once optimum conditions return.https://www.mdpi.com/2076-0817/8/3/95Babesiainvasionmalariapersistencepopulation structure
collection DOAJ
language English
format Article
sources DOAJ
author Cheryl A Lobo
Jeny R Cursino-Santos
Manpreet Singh
Marilis Rodriguez
spellingShingle Cheryl A Lobo
Jeny R Cursino-Santos
Manpreet Singh
Marilis Rodriguez
<i>Babesia divergens</i>: A Drive to Survive
Pathogens
Babesia
invasion
malaria
persistence
population structure
author_facet Cheryl A Lobo
Jeny R Cursino-Santos
Manpreet Singh
Marilis Rodriguez
author_sort Cheryl A Lobo
title <i>Babesia divergens</i>: A Drive to Survive
title_short <i>Babesia divergens</i>: A Drive to Survive
title_full <i>Babesia divergens</i>: A Drive to Survive
title_fullStr <i>Babesia divergens</i>: A Drive to Survive
title_full_unstemmed <i>Babesia divergens</i>: A Drive to Survive
title_sort <i>babesia divergens</i>: a drive to survive
publisher MDPI AG
series Pathogens
issn 2076-0817
publishDate 2019-07-01
description <i>Babesia divergens</i> is an obligate intracellular protozoan parasite that causes zoonotic disease. Central to its pathogenesis is the ability of the parasite to invade host red blood cells of diverse species, and, once in the host blood stream, to manipulate the composition of its population to allow it to endure unfavorable conditions. Here we will review key in vitro studies relating to the survival strategies that <i>B. divergens</i> adopts during its intraerythrocytic development to persist and how proliferation is restored in the parasite population once optimum conditions return.
topic Babesia
invasion
malaria
persistence
population structure
url https://www.mdpi.com/2076-0817/8/3/95
work_keys_str_mv AT cherylalobo ibabesiadivergensiadrivetosurvive
AT jenyrcursinosantos ibabesiadivergensiadrivetosurvive
AT manpreetsingh ibabesiadivergensiadrivetosurvive
AT marilisrodriguez ibabesiadivergensiadrivetosurvive
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