Tuning G-Quadruplex Nanostructures with Lipids. Towards Designing Hybrid Scaffolds for Oligonucleotide Delivery

Tuning G-Quadruplex Nanostructures with Lipids. Towards Designing Hybrid Scaffolds for Oligonucleotide Delivery

Two G-quadruplex forming oligonucleotides [d(TG<sub>4</sub>T)<sub>4</sub> and d(TG<sub>6</sub>T)<sub>4</sub>] were selected as two tetramolecular quadruplex nanostructures because of their demonstrated ability to be modified with hydrophobic molecules....

Full description

Bibliographic Details
Main Authors: Santiago Grijalvo, Anna Clua, Marc Eres, Raimundo Gargallo, Ramon Eritja
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
antisense oligonucleotides
circular dichroism
G-quadruplex
gene delivery
gene transfection
lipids
Online Access:https://www.mdpi.com/1422-0067/22/1/121

Similar Items

Similar Items