Development of a High-Throughput Method to Study the Inhibitory Effect of Phytochemicals on Trimethylamine Formation

Development of a High-Throughput Method to Study the Inhibitory Effect of Phytochemicals on Trimethylamine Formation

Choline is metabolized by the gut microbiota into trimethylamine (TMA), the precursor of pro-atherosclerotic molecule trimethylamine N-oxide (TMAO). A reduction in TMA formation has shown cardioprotective effects, and some phytochemicals may reduce TMA formation. This study aimed to develop an optim...

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Bibliographic Details
Main Authors: Lisard Iglesias-Carres, Lauren A. Essenmacher, Kathryn C. Racine, Andrew P. Neilson
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Nutrients
Subjects:
atherosclerosis
gallic acid
chlorogenic acid
microbiota
trimethylamine
Online Access:https://www.mdpi.com/2072-6643/13/5/1466

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