Carnosine's effect on amyloid fibril formation and induced cytotoxicity of lysozyme.

Carnosine's effect on amyloid fibril formation and induced cytotoxicity of lysozyme.

Carnosine, a common dipeptide in mammals, has previously been shown to dissemble alpha-crystallin amyloid fibrils. To date, the dipeptide's anti-fibrillogensis effect has not been thoroughly characterized in other proteins. For a more complete understanding of carnosine's mechanism of acti...

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Bibliographic Details
Main Authors: Josephine W Wu, Kuan-Nan Liu, Su-Chun How, Wei-An Chen, Chia-Min Lai, Hwai-Shen Liu, Chaur-Jong Hu, Steven S-S Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3859581?pdf=render

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