Cold-inducible protein RBM3 protects neuroblastoma cells from retinoic acid-induced apoptosis via AMPK, p38 and JNK signaling

Cold-inducible protein RBM3 protects neuroblastoma cells from retinoic acid-induced apoptosis via AMPK, p38 and JNK signaling

As a result of vitamin A abuse, excessive retinoic acid can induce apoptosis in neural cells. Mild-hypothermia and cold-inducible protein RBM3 protect neural cells from apoptosis. However, whether hypothermia/RBM3 protect neural cells from retinoic acid-induced apoptosis remains unclear. The SH-SY5Y...

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Bibliographic Details
Main Authors: Shuang-Ping Ma, Fei Ju, Ya-Ping Zhang, Xiang Shi, Rui-Juan Zhuang, Han Xue, Jian Ma, Lei Wang, Bin-Feng Cheng, Hong Cao, Zhi-Wei Feng, Mian Wang, Hai-Jie Yang
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Journal of Functional Foods
Subjects:
Vitamin A
Retinoic acid
Mild hypothermia
RBM3
Apoptosis
Signaling pathways
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617302918

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