A carcinogenic trigger to study the function of tumor suppressor genes in Schmidtea mediterranea

A carcinogenic trigger to study the function of tumor suppressor genes in Schmidtea mediterranea

Planarians have been long known for their regenerative ability, which hinges on pluripotency. Recently, however, the planarian model has been successfully established for routine toxicological screens aimed to assess overproliferation, mutagenicity and tumorigenesis. In this study, we focused on pla...

Full description

Bibliographic Details
Main Authors: Andromeda Van Roten, Amal Zohir Abo-Zeid Barakat, Annelies Wouters, Thao Anh Tran, Stijn Mouton, Jean-Paul Noben, Luca Gentile, Karen Smeets
Format: Article
Language:English
Published: The Company of Biologists 2018-09-01
Series:Disease Models & Mechanisms
Subjects:
Planarian
Cadmium
Carcinogens
Matrix-metalloproteinases
Stem cells
Tumor suppressor genes
Online Access:http://dmm.biologists.org/content/11/9/dmm032573

Similar Items

Similar Items