Estimating effects of rare haplotypes on failure time using a penalized Cox proportional hazards regression model

Estimating effects of rare haplotypes on failure time using a penalized Cox proportional hazards regression model

<p>Abstract</p> <p>Background</p> <p>This paper describes a likelihood approach to model the relation between failure time and haplotypes in studies with unrelated individuals where haplotype phase is unknown, while dealing with the problem of unstable estimates due to...

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Bibliographic Details
Main Authors: Tanck Michael WT, Jukema J Wouter, Zwinderman Aeilko H, Souverein Olga W
Format: Article
Language:English
Published: BMC 2008-01-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/9/9

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