The nucleotide addition cycle of RNA polymerase is controlled by two molecular hinges in the Bridge Helix domain
<p>Abstract</p> <p>Background</p> <p>Cellular RNA polymerases (RNAPs) are complex molecular machines that combine catalysis with concerted conformational changes in the active center. Previous work showed that kinking of a hinge region near the C-terminus of the Bridge...
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| Format: | Article |
| Language: | English |
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BMC
2010-10-01
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| Series: | BMC Biology |
| Online Access: | http://www.biomedcentral.com/1741-7007/8/134 |