PACAP and its receptors in cranial arteries and mast cells

Abstract Background In migraineurs pituitary adenylate cyclase activating peptide1–38 (PACAP1–38) is a potent migraine provoking substance and the accompanying long lasting flushing suggests degranulation of mast cells. Infusion of the closely related vasoactive intestinal peptide (VIP) either induc...

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Bibliographic Details
Main Authors: Inger Jansen-Olesen, Sara Hougaard Pedersen
Format: Article
Language:English
Published: BMC 2018-02-01
Series:The Journal of Headache and Pain
Subjects:
VIP
Online Access:http://link.springer.com/article/10.1186/s10194-017-0822-2