The Development of Whole Sporozoite Vaccines for Plasmodium falciparum Malaria

The Development of Whole Sporozoite Vaccines for Plasmodium falciparum Malaria

Each year malaria kills hundreds of thousands of people and infects hundreds of millions of people despite current control measures. An effective malaria vaccine will likely be necessary to aid in malaria eradication. Vaccination using whole sporozoites provides an increased repertoire of immunogens...

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Bibliographic Details
Main Authors: Leslie S. Itsara, Yaxian Zhou, Julie Do, Alexis M. Grieser, Ashley M. Vaughan, Anil K. Ghosh
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
Plasmodium falciparum
malaria
whole sporozoite vaccines
genetically attenuated parasite
radiation attenuated sporozoite
in vitro culturing
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02748/full

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