Exome-Wide Association Study Reveals Several Susceptibility Genes and Pathways Associated With Acute Coronary Syndromes in Han Chinese

Exome-Wide Association Study Reveals Several Susceptibility Genes and Pathways Associated With Acute Coronary Syndromes in Han Chinese

Genome-wide association studies have identified more than 150 susceptibility loci for coronary artery disease (CAD); however, there is still a large proportion of missing heritability remaining to be investigated. This study sought to identify population-based genetic variation associated with acute...

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Bibliographic Details
Main Authors: Qiwen Zheng, Yan Zhang, Jie Jiang, Jia Jia, Fangfang Fan, Yanjun Gong, Zhi Wang, Qiuping Shi, Dafang Chen, Yong Huo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Genetics
Subjects:
exome-wide association study
acute coronary syndrome
control selection strategy
risk prediction tool
gene-based analysis
pathway-based analysis
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00336/full

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https://www.frontiersin.org/article/10.3389/fgene.2020.00336/full

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