Rabies Virus Infection Induces Microtubule Depolymerization to Facilitate Viral RNA Synthesis by Upregulating HDAC6

Rabies Virus Infection Induces Microtubule Depolymerization to Facilitate Viral RNA Synthesis by Upregulating HDAC6

Rabies virus (RABV) is the cause of rabies, and is associated with severe neurological symptoms, high mortality rate, and a serious threat to human health. Although cellular tubulin has recently been identified to be incorporated into RABV particles, the effects of RABV infection on the microtubule...

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Bibliographic Details
Main Authors: Jin-Yan Gu, Min Liao, Jie Zan, Song Liu, Dong-Nan Sun, Kai-Kun Mo, Yan Yan, Juan Liu, Bo-Li Hu, Ji-Yong Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
rabies virus
matrix protein
microtubule depolymerization
viral RNA synthesis
acetylated modification
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00146/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00146/full

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