Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model

<p>Abstract</p> <p>Background</p> <p>Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservation present in these protein sequences presumably are due to select...

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Bibliographic Details
Main Authors: Liu Jun S, Neuwald Andrew F
Format: Article
Language:English
Published: BMC 2004-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/5/157