The receptor for urokinase regulates TLR2 mediated inflammatory responses in neutrophils.

The urokinase-type plasminogen activator receptor (uPAR), a glycosylphosphatidylinositol (GPI) anchored membrane protein, regulates urokinase (uPA) protease activity, chemotaxis, cell-cell interactions, and phagocytosis of apoptotic cells. uPAR expression is increased in cytokine or bacteria activat...

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Bibliographic Details
Main Authors: Gang Liu, Yanping Yang, Shanzhong Yang, Sami Banerjee, Andressa De Freitas, Arnaud Friggeri, Kasey I Davis, Edward Abraham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3187811?pdf=render

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