An Update on the Role of Nrf2 in Respiratory Disease: Molecular Mechanisms and Therapeutic Approaches

An Update on the Role of Nrf2 in Respiratory Disease: Molecular Mechanisms and Therapeutic Approaches

Nuclear factor erythroid 2-related factor (Nrf2) is a transcriptional activator of the cell protection gene that binds to the antioxidant response element (ARE). Therefore, Nrf2 protects cells and tissues from oxidative stress. Normally, Kelch-like ECH-associated protein 1 (Keap1) inhibits the activ...

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Bibliographic Details
Main Authors: Jooyeon Lee, Jimin Jang, Sung-Min Park, Se-Ran Yang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
Nrf2
keap1
oxidative stress
ROS
respiratory diseases
lung
Online Access:https://www.mdpi.com/1422-0067/22/16/8406

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