Nasunin, a new player in the field of osteoblast protection against oxidative stress

Nasunin, a new player in the field of osteoblast protection against oxidative stress

This study investigated whether nasunin, the major component of anthocyanin pigment of eggplant (Solanum melongena L.), known for its antioxidant effects, counteracts tert-butyl hydroperoxide (t-BHP)-induced oxidative damage in MC3T3-E1 osteoblastic cells. Pretreatment with purified nasunin (10−10–1...

Full description

Bibliographic Details
Main Authors:	Lavinia Casati, Francesca Pagani, Pier Carlo Braga, Roberto Lo Scalzo, Valeria Sibilia
Format:	Article
Language:	English
Published:	Elsevier 2016-05-01
Series:	Journal of Functional Foods
Subjects:	Nasunin Osteoblasts Oxidative stress Osteoblastic dysfunction Phosphoinositide 3-kinase/AKT pathway
Online Access:	http://www.sciencedirect.com/science/article/pii/S1756464616300275

Similar Items

A specific role for phosphoinositide 3-kinase and AKT in osteoblasts?
by: Imelda Mary McGonnell, et al.
Published: (2012-07-01)

Regulation of Osteoblast Differentiation by Cytokine Networks
by: Dulshara Sachini Amarasekara, et al.
Published: (2021-03-01)

Monotropein attenuates oxidative stress via Akt/mTOR-mediated autophagy in osteoblast cells
by: Yao Shi, et al.
Published: (2020-01-01)

Food for Bone: Evidence for a Role for Delta-Tocotrienol in the Physiological Control of Osteoblast Migration
by: Lavinia Casati, et al.
Published: (2020-06-01)

Different Expression and Localization of Phosphoinositide Specific Phospholipases C in Human Osteoblasts, Osteosarcoma Cell Lines, Ewing Sarcoma and Synovial Sarcoma
by: V.Vasco, et al.
Published: (2017-06-01)

The extract of concentrated growth factor enhances osteogenic activity of osteoblast through PI3K/AKT pathway and promotes bone regeneration in vivo
by: Kai Dong, et al.
Published: (2021-08-01)

Resveratrol Inhibits the Epidermal Growth Factor-Induced Migration of Osteoblasts: the Suppression of SAPK/JNK and Akt
by: Tetsu Kawabata, et al.
Published: (2017-10-01)

B. Abortus Modulates Osteoblast Function Through the Induction of Autophagy
by: Ayelén Ivana Pesce Viglietti, et al.
Published: (2018-12-01)

Effect and mechanism of neurotrophin 3 on inhibiting dexamethasoneinduced mouse MC3T3-E1 osteoblast apoptosis
by: Ping Fan, et al.
Published: (2020-11-01)

Osteoblasts derived from mouse mandible enhance tumor growth of prostate cancer more than osteoblasts derived from long bone
by: Matthew R. Eber, et al.
Published: (2021-02-01)

Characterization and antioxidant activity of semi-purified extracts and pure delphinidin-glycosides from eggplant peel (Solanum melongena L.)
by: Pier Carlo Braga, et al.
Published: (2016-01-01)

Signaling Pathway and Transcriptional Regulation in Osteoblasts during Bone Healing: Direct Involvement of Hydroxyapatite as a Biomaterial
by: Junaidi Khotib, et al.
Published: (2021-06-01)

Effect of GLP-1 agonist on osteoblast proliferation and related signaling pathways
by: Jian-Qiang Gao, et al.
Published: (2018-09-01)

The effects of electromagnetic wave stimulation (EMS) on osteoblast differentiation and activity
by: Pauly, Katherine L.
Published: (2020)

Boldine Ameliorates Estrogen Deficiency-Induced Bone Loss via Inhibiting Bone Resorption
by: Kun Chen, et al.
Published: (2018-09-01)

Signaling pathways regulating the specification and differentiation of the osteoblast lineage
by: Hironori Hojo, et al.
Published: (2015-06-01)

Regulating effect of borosilicate bioglass extract on the osteoblast proliferation activity and osteogenesis signaling pathway function
by: Xiao-Hui He, et al.
Published: (2017-11-01)

Experimental study about the regulating effect of puerarin on osteoblast proliferation in vitro and related signal pathway expression
by: Hong-Sheng Hu, et al.
Published: (2017-04-01)

Icariin, but Not Genistein, Exerts Osteogenic and Anti-apoptotic Effects in Osteoblastic Cells by Selective Activation of Non-genomic ERα Signaling
by: Ming-Xian Ho, et al.
Published: (2018-05-01)

The mTORC2 Regulator Homer1 Modulates Protein Levels and Sub-Cellular Localization of the CaSR in Osteoblast-Lineage Cells
by: Mark S. Rybchyn, et al.
Published: (2021-06-01)

The effect of caffeine on osteoblast proliferation after tooth extraction in Wistar rats
by: Budi Yuwono
Published: (2006-03-01)

Preparation of a Fucoidan-Grafted Hyaluronan Composite Hydrogel for the Induction of Osteoblast Differentiation in Osteoblast-Like Cells
by: Fu-Yin Hsu, et al.
Published: (2021-03-01)

Porcine bone collagen peptides promote osteoblast proliferation and differentiation by activating the PI3K/Akt signaling pathway
by: Lingyu Zhu, et al.
Published: (2020-01-01)

Rhizome drynariae extract regulates osteoblast viability and proliferation as well as related gene expression: an experimental study
by: Chun-Li Meng
Published: (2017-04-01)

The effects of various mouthwashes on osteoblast precursor cells
by: Song In-Seok, et al.
Published: (2019-07-01)

Ricolinostat (ACY-1215) inhibits VEGF expression via PI3K/AKT pathway and promotes apoptosis in osteoarthritic osteoblasts
by: Lei Li, et al.
Published: (2019-10-01)

Microcurrent Stimulation Triggers MAPK Signaling and TGF-β1 Release in Fibroblast and Osteoblast-Like Cell Lines
by: Evangelia Konstantinou, et al.
Published: (2020-08-01)

Synthetic Function and Regulation of Osteoblasts: Current Knowledge and Applications
by: Peter J. Millett, et al.
Published: (2020-12-01)

Towards specific DNA aptamers which bind and inhibit WWP1 HECT ubiquitin ligase in the osteoblast
by: Tucker, Wesley Owen
Published: (2014)

Anagliptin stimulates osteoblastic cell differentiation and mineralization
by: Chao Dong, et al.
Published: (2020-09-01)

VNUT/SLC17A9, a vesicular nucleotide transporter, regulates osteoblast differentiation
by: Asako Inoue, et al.
Published: (2020-08-01)

Osteoblast Role in Rheumatic Diseases
by: Addolorata Corrado, et al.
Published: (2017-06-01)

Effect of puerarin on osteoblast proliferation in vitro and Wnt/ β-catenin signaling pathway expression
by: Zhi Luo1, et al.
Published: (2017-05-01)

Osteoblastogenesis and Role of Osteoblasts in Calcıum Homeostasis and Remodeling of Bone
by: Neslihan Başcıl Tütüncü
Published: (2008-05-01)

Influence of Ceramic Debris on Osteoblast Behaviors: An In Vivo Study
by: Guo‐jing Sun, et al.
Published: (2019-10-01)

p38 MAPK signalling in osteoblast differentiation
by: Edgardo eRodríguez-Carballo, et al.
Published: (2016-05-01)

Osteoblastic and Osteoclastic Metastases in a Single Vertebra-A Rare Presentation
by: Gian Chand, et al.
Published: (2015-02-01)

The Effect of Strontium-Substituted Hydroxyapatite Nanofibrous Matrix on Osteoblast Proliferation and Differentiation
by: Shiao-Wen Tsai, et al.
Published: (2021-08-01)

Osteoblast-Osteoclast Communication and Bone Homeostasis
by: Jung-Min Kim, et al.
Published: (2020-09-01)

Effect of lactoferrin on rat osteoblast proliferation
by: Jun Wang, et al.
Published: (2016-10-01)