The primary cilium directs osteopontin-induced migration of mesenchymal stem cells by regulating CD44 signaling and Cdc42 activation

The primary cilium directs osteopontin-induced migration of mesenchymal stem cells by regulating CD44 signaling and Cdc42 activation

The primary cilium acts as a sensory organelle with diverse receptors and ion channels to detect extracellular cues and regulate cellular functions, including cell migration. The migration of mesenchymal stem cells (MSCs) to bone remodeling sites is important for bone homeostasis. Recently, we have...

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Bibliographic Details
Main Authors: Mi Nam Lee, Ju Han Song, Sin-Hye Oh, Nguyen Thi Tham, Jung-Woo Kim, Jin-Woo Yang, Eung-Sam Kim, Jeong-Tae Koh
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Stem Cell Research
Subjects:
Primary cilium
Mesenchymal stem cells
Osteopontin
CD44
Cdc42
Migration
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120301021

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http://www.sciencedirect.com/science/article/pii/S1873506120301021

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