Modulation of experimental herpes encephalitis-associated neurotoxicity through sulforaphane treatment.
Reactive oxygen species (ROS) produced by brain-infiltrating macrophages and neutrophils, as well as resident microglia, are pivotal to pathogen clearance during viral brain infection. However, unchecked free radical generation is also responsible for damage to and cytotoxicity of critical host tiss...
Main Authors: | Scott J Schachtele, Shuxian Hu, James R Lokensgard |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3338688?pdf=render |
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