Modulation of experimental herpes encephalitis-associated neurotoxicity through sulforaphane treatment.

Reactive oxygen species (ROS) produced by brain-infiltrating macrophages and neutrophils, as well as resident microglia, are pivotal to pathogen clearance during viral brain infection. However, unchecked free radical generation is also responsible for damage to and cytotoxicity of critical host tiss...

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Bibliographic Details
Main Authors: Scott J Schachtele, Shuxian Hu, James R Lokensgard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338688?pdf=render

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