Piezo 1 activation facilitates cholangiocarcinoma metastasis via Hippo/YAP signaling axis

Tumor metastasis is one of the major factors for the high mortality in cholangiocarcinoma (CCA), but its underlying mechanisms are not fully understood. Here, we report that Piezo-type mechanosensitive ion channel component 1 (Piezo 1) is detected to be significantly upregulated in CCA tissues, whic...

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Bibliographic Details
Main Authors: Biqiang Zhu, Wei Qian, Chaoqun Han, Tao Bai, Xiaohua Hou
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121000615