Intravenous ivabradine versus placebo in patients with low cardiac output syndrome treated by dobutamine after elective coronary artery bypass surgery: a phase 2 exploratory randomized controlled trial

Intravenous ivabradine versus placebo in patients with low cardiac output syndrome treated by dobutamine after elective coronary artery bypass surgery: a phase 2 exploratory randomized controlled trial

Abstract Background Low cardiac output syndrome (LCOS) is a severe condition which can occur after cardiac surgery, especially among patients with pre-existing left ventricular dysfunction. Dobutamine, its first-line treatment, is associated with sinus tachycardia. This study aims to assess the abil...

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Bibliographic Details
Main Authors: Lee S. Nguyen, Pierre Squara, Julien Amour, Daniel Carbognani, Kamel Bouabdallah, Stéphane Thierry, Caroline Apert-Verneuil, Aurélie Moyne, Bernard Cholley
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Critical Care
Subjects:
Cardiac surgery
Low cardiac output syndrome
Cardiogenic shock
Postoperative atrial fibrillation
Coronary artery bypass graft
Systolic heart failure
Online Access:http://link.springer.com/article/10.1186/s13054-018-2124-8

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