Structure-function analysis of MmpL7-mediated lipid transport in mycobacteria

Structure-function analysis of MmpL7-mediated lipid transport in mycobacteria

Mycobacterial membrane protein Large (MmpL7) is a Resistance-Nodulation-Division (RND) family transporter required for the export of the virulence lipid, phthiocerol dimycocerosate (PDIM), in Mycobacterium tuberculosis. Using a null mutant of the related, vaccine strain Mycobacterium bovis BCG, we s...

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Bibliographic Details
Main Authors: Nabiela Moolla, Rebeca Bailo, Robert Marshall, Vassiliy N. Bavro, Apoorva Bhatt
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:The Cell Surface
Subjects:
Mycobacterium tuberculosis
MmpL
PDIM
Lipid transport
RND transporters
Online Access:http://www.sciencedirect.com/science/article/pii/S2468233021000153

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