Low-level lead exposure increases systolic arterial pressure and endothelium-derived vasodilator factors in rat aortas.

Chronic lead exposure induces hypertension and alters endothelial function. However, treatment with low lead concentrations was not yet explored. We analyzed the effects of 7 day exposure to low lead concentrations on endothelium-dependent responses. Wistar rats were treated with lead (1st dose 4 µg...

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Main Authors: Jonaina Fiorim, Rogério F Ribeiro Júnior, Edna A Silveira, Alessandra S Padilha, Marcos Vinícius A Vescovi, Honério C de Jesus, Ivanita Stefanon, Mercedes Salaices, Dalton V Vassallo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3045404?pdf=render