Oral ezatiostat HCl (Telintra<sup>®</sup>, TLK199) and Idiopathic Chronic Neutropenia (ICN): a case report of complete response of a patient with G-CSF resistant ICN following treatment with ezatiostat, a glutathione S-transferase P1-1 (GSTP1-1) inhibitor

Oral ezatiostat HCl (Telintra<sup>®</sup>, TLK199) and Idiopathic Chronic Neutropenia (ICN): a case report of complete response of a patient with G-CSF resistant ICN following treatment with ezatiostat, a glutathione S-transferase P1-1 (GSTP1-1) inhibitor

<p>Abstract</p> <p>Idiopathic chronic neutropenia (ICN) describes a heterogeneous group of hematologic diseases characterized by low circulating neutrophil levels often associated with recurrent fevers, chronic mucosal inflammation, and severe systemic infections. The severity and...

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Bibliographic Details
Main Authors: Lyons Roger M, Wilks Sharon T, Young Shelby, Brown Gail L
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Journal of Hematology & Oncology
Subjects:
idiopathic chronic neutropenia
ezatiostat
Online Access:http://www.jhoonline.org/content/4/1/43

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