Methamphetamine decreases dentate gyrus stem cell self-renewal and shifts the differentiation towards neuronal fate

Methamphetamine (METH) is a highly addictive psychostimulant drug of abuse that negatively interferes with neurogenesis. In fact, we have previously shown that METH triggers stem/progenitor cell death and decreases neuronal differentiation in the dentate gyrus (DG). Still, little is known regarding...

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Bibliographic Details
Main Authors: Sofia Baptista, Charlène Lasgi, Caroline Benstaali, Nuno Milhazes, Fernanda Borges, Carlos Fontes-Ribeiro, Fabienne Agasse, Ana Paula Silva
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506114000920