Epidemiological evidence for work load as a risk factor for osteoarthritis of the hip: a systematic review.

<h4>Objective</h4>Osteoarthritis of the hip (OA) is a common degenerative disorder of the joint cartilage that presents a major public health problem worldwide. While intrinsic risk factors (e.g, body mass and morphology) have been identified, external risk factors are not well understoo...

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Main Authors: Sandra I Sulsky, Laura Carlton, Frank Bochmann, Rolf Ellegast, Ulrich Glitsch, Bernd Hartmann, Dirk Pallapies, D Seidel, Yi Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22348095/?tool=EBI
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spelling doaj-5d3491a794bb48f29258e648eea060e42021-03-04T01:04:40ZengPublic Library of Science (PLoS)PLoS ONE1932-62032012-01-0172e3152110.1371/journal.pone.0031521Epidemiological evidence for work load as a risk factor for osteoarthritis of the hip: a systematic review.Sandra I SulskyLaura CarltonFrank BochmannRolf EllegastUlrich GlitschBernd HartmannDirk PallapiesD SeidelYi Sun<h4>Objective</h4>Osteoarthritis of the hip (OA) is a common degenerative disorder of the joint cartilage that presents a major public health problem worldwide. While intrinsic risk factors (e.g, body mass and morphology) have been identified, external risk factors are not well understood. In this systematic review, the evidence for workload as a risk factor for hip OA is summarized and used to derive recommendations for prevention and further research.<h4>Methods</h4>Epidemiological studies on workload or occupation and osteoarthritis of the hip were identified through database and bibliography searches. Using pre-defined quality criteria, 30 studies were selected for critical evaluation; six of these provided quantitative exposure data.<h4>Results</h4>Study results were too heterogeneous to develop pooled risk estimates by specific work activities. The weight of evidence favors a graded association between long-term exposure to heavy lifting and risk of hip OA. Long-term exposure to standing at work might also increase the risk of hip OA.<h4>Conclusions</h4>It is not possible to estimate a quantitative dose-response relationship between workload and hip OA using existing data, but there is enough evidence available to identify job-related heavy lifting and standing as hazards, and thus to begin developing recommendations for preventing hip OA by limiting the amount and duration of these activities. Future research to identify specific risk factors for work-related hip OA should focus on implementing rigorous study methods with quantitative exposure measures and objective diagnostic criteria.https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22348095/?tool=EBI
collection DOAJ
language English
format Article
sources DOAJ
author Sandra I Sulsky
Laura Carlton
Frank Bochmann
Rolf Ellegast
Ulrich Glitsch
Bernd Hartmann
Dirk Pallapies
D Seidel
Yi Sun
spellingShingle Sandra I Sulsky
Laura Carlton
Frank Bochmann
Rolf Ellegast
Ulrich Glitsch
Bernd Hartmann
Dirk Pallapies
D Seidel
Yi Sun
Epidemiological evidence for work load as a risk factor for osteoarthritis of the hip: a systematic review.
PLoS ONE
author_facet Sandra I Sulsky
Laura Carlton
Frank Bochmann
Rolf Ellegast
Ulrich Glitsch
Bernd Hartmann
Dirk Pallapies
D Seidel
Yi Sun
author_sort Sandra I Sulsky
title Epidemiological evidence for work load as a risk factor for osteoarthritis of the hip: a systematic review.
title_short Epidemiological evidence for work load as a risk factor for osteoarthritis of the hip: a systematic review.
title_full Epidemiological evidence for work load as a risk factor for osteoarthritis of the hip: a systematic review.
title_fullStr Epidemiological evidence for work load as a risk factor for osteoarthritis of the hip: a systematic review.
title_full_unstemmed Epidemiological evidence for work load as a risk factor for osteoarthritis of the hip: a systematic review.
title_sort epidemiological evidence for work load as a risk factor for osteoarthritis of the hip: a systematic review.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2012-01-01
description <h4>Objective</h4>Osteoarthritis of the hip (OA) is a common degenerative disorder of the joint cartilage that presents a major public health problem worldwide. While intrinsic risk factors (e.g, body mass and morphology) have been identified, external risk factors are not well understood. In this systematic review, the evidence for workload as a risk factor for hip OA is summarized and used to derive recommendations for prevention and further research.<h4>Methods</h4>Epidemiological studies on workload or occupation and osteoarthritis of the hip were identified through database and bibliography searches. Using pre-defined quality criteria, 30 studies were selected for critical evaluation; six of these provided quantitative exposure data.<h4>Results</h4>Study results were too heterogeneous to develop pooled risk estimates by specific work activities. The weight of evidence favors a graded association between long-term exposure to heavy lifting and risk of hip OA. Long-term exposure to standing at work might also increase the risk of hip OA.<h4>Conclusions</h4>It is not possible to estimate a quantitative dose-response relationship between workload and hip OA using existing data, but there is enough evidence available to identify job-related heavy lifting and standing as hazards, and thus to begin developing recommendations for preventing hip OA by limiting the amount and duration of these activities. Future research to identify specific risk factors for work-related hip OA should focus on implementing rigorous study methods with quantitative exposure measures and objective diagnostic criteria.
url https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22348095/?tool=EBI
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