Epoxypukalide induces proliferation and protects against cytokine-mediated apoptosis in primary cultures of pancreatic β-cells.

There is an urgency to find new treatments for the devastating epidemic of diabetes. Pancreatic β-cells viability and function are impaired in the two most common forms of diabetes, type 1 and type 2. Regeneration of pancreatic β-cells has been proposed as a potential therapy for diabetes. In a prel...

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Bibliographic Details
Main Authors: José Francisco López-Acosta, José Luis Moreno-Amador, Margarita Jiménez-Palomares, Ana R Díaz-Marrero, Mercedes Cueto, Germán Perdomo, Irene Cózar-Castellano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3534672?pdf=render