Downregulation of Calcineurin Gene Is Associated with Glucantime(®) Resiatance in Leishmania infantum

Downregulation of Calcineurin Gene Is Associated with Glucantime(®) Resiatance in Leishmania infantum

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Background: Pentavalent antimonials are the first line drugs for the treatment of leishmaniasis. Unresponsiveness of Leishmania spp. to antimonial drugs is a serious problem in some endemic areas. Investigations on molecular mechanisms involved in drug resistance are essential for monitoring an...

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Bibliographic Details
Main Authors:	Mohammad Bagher Khadem Erfan, Mehdi Mohebali, Elham Kazemi-Rad, Homa Hajjaran, Gholamhossein Edrissian, Setareh Mamishi, Mojtaba Saffari, Reza Raoofian, Mansour Heidari
Format:	Article
Language:	English
Published:	Tehran University of Medical Sciences 2013-09-01
Series:	Iranian Journal of Parasitology
Subjects:	Antimonial resistance Calcineurin gene Leishmania infantum Real-time RT-PCR cDNA-AFLP
Online Access:	https://ijpa.tums.ac.ir/index.php/ijpa/article/view/483

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