Remitting - Relapsing Polyneuropathy In Juvenile Metachromatic Leukodystrophy

Remitting - Relapsing Polyneuropathy In Juvenile Metachromatic Leukodystrophy

A five-year-old girl manifested with acute relapsing polyradiculo-neuropathy. Elevated cerebrospinal fluid proteins, electro-physiological evidence of conduction block and remitting course suggested possible acquired demyelinating radiculoneuropathy. However, intellectual deterioration during follo...

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Main Authors: Taly AB, Santosh V, Balamurugan N, Arunodaya GR, Christopher R, Jayakumar PN
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2004-01-01
Series:Annals of Indian Academy of Neurology
Online Access:http://www.annalsofian.org/article.asp?issn=0972-2327;year=2004;volume=7;issue=4;spage=543;epage=548;aulast=Taly;type=0
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spelling doaj-5d2aac93734b4e548d12aea40cbbd8542020-11-24T23:16:57ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492004-01-0174543548Remitting - Relapsing Polyneuropathy In Juvenile Metachromatic LeukodystrophyTaly ABSantosh VBalamurugan NArunodaya GRChristopher RJayakumar PNA five-year-old girl manifested with acute relapsing polyradiculo-neuropathy. Elevated cerebrospinal fluid proteins, electro-physiological evidence of conduction block and remitting course suggested possible acquired demyelinating radiculoneuropathy. However, intellectual deterioration during follow up, evidence of extensive, symmetrical and periventricular demyelination on MRI of brain and metachromatic on sural nerve biopsy led to the diagnosis of metachromatic leukodystrophy (MLD). Inherited neuropathies such as MLD may occasionally present atypically in the early stages. Recognition of this variation has considerable therapeutic and prognostic significance.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2004;volume=7;issue=4;spage=543;epage=548;aulast=Taly;type=0
collection DOAJ
language English
format Article
sources DOAJ
author Taly AB
Santosh V
Balamurugan N
Arunodaya GR
Christopher R
Jayakumar PN
spellingShingle Taly AB
Santosh V
Balamurugan N
Arunodaya GR
Christopher R
Jayakumar PN
Remitting - Relapsing Polyneuropathy In Juvenile Metachromatic Leukodystrophy
Annals of Indian Academy of Neurology
author_facet Taly AB
Santosh V
Balamurugan N
Arunodaya GR
Christopher R
Jayakumar PN
author_sort Taly AB
title Remitting - Relapsing Polyneuropathy In Juvenile Metachromatic Leukodystrophy
title_short Remitting - Relapsing Polyneuropathy In Juvenile Metachromatic Leukodystrophy
title_full Remitting - Relapsing Polyneuropathy In Juvenile Metachromatic Leukodystrophy
title_fullStr Remitting - Relapsing Polyneuropathy In Juvenile Metachromatic Leukodystrophy
title_full_unstemmed Remitting - Relapsing Polyneuropathy In Juvenile Metachromatic Leukodystrophy
title_sort remitting - relapsing polyneuropathy in juvenile metachromatic leukodystrophy
publisher Wolters Kluwer Medknow Publications
series Annals of Indian Academy of Neurology
issn 0972-2327
1998-3549
publishDate 2004-01-01
description A five-year-old girl manifested with acute relapsing polyradiculo-neuropathy. Elevated cerebrospinal fluid proteins, electro-physiological evidence of conduction block and remitting course suggested possible acquired demyelinating radiculoneuropathy. However, intellectual deterioration during follow up, evidence of extensive, symmetrical and periventricular demyelination on MRI of brain and metachromatic on sural nerve biopsy led to the diagnosis of metachromatic leukodystrophy (MLD). Inherited neuropathies such as MLD may occasionally present atypically in the early stages. Recognition of this variation has considerable therapeutic and prognostic significance.
url http://www.annalsofian.org/article.asp?issn=0972-2327;year=2004;volume=7;issue=4;spage=543;epage=548;aulast=Taly;type=0
work_keys_str_mv AT talyab remittingrelapsingpolyneuropathyinjuvenilemetachromaticleukodystrophy
AT santoshv remittingrelapsingpolyneuropathyinjuvenilemetachromaticleukodystrophy
AT balamurugann remittingrelapsingpolyneuropathyinjuvenilemetachromaticleukodystrophy
AT arunodayagr remittingrelapsingpolyneuropathyinjuvenilemetachromaticleukodystrophy
AT christopherr remittingrelapsingpolyneuropathyinjuvenilemetachromaticleukodystrophy
AT jayakumarpn remittingrelapsingpolyneuropathyinjuvenilemetachromaticleukodystrophy
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