LncRNA HOTAIR knockdown inhibits glycolysis by regulating miR-130a-3p/HIF1A in hepatocellular carcinoma under hypoxia

LncRNA HOTAIR knockdown inhibits glycolysis by regulating miR-130a-3p/HIF1A in hepatocellular carcinoma under hypoxia

High rate of glycolysis supports hepatocellular carcinoma (HCC) cell growth even in a hypoxic environment. However, the mechanism underlying glycolysis under hypoxia remains largely unknown. Long noncoding RNAs (lncRNAs) play essential roles in regulating glucose metabolism in cancers. This study ai...

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Bibliographic Details
Main Authors: Mingxing Hu, Qiang Fu, Chan Jing, Xu Zhang, Tao Qin, Yanfeng Pan
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Hepatocellular carcinoma
Glycolysis
Hypoxia
HOTAIR
miR-130a-3p
HIF1A
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219353259

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