The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease

The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease

The chemokine receptor CXCR4 and its ligand CXCL12 play an important homeostatic function by mediating the homing of progenitor cells in the bone marrow and regulating their mobilization into peripheral tissues upon injury or stress. Although the CXCL12/CXCR4 interaction has long been regarded as a...

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Bibliographic Details
Main Authors: Yvonne eDöring, Lukas ePawig, Christian eWeber, Heidi eNoels
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Physiology
Subjects:
Atherosclerosis
Myocardial Infarction
CXCR4
cardiovascular disease
chemokine receptor
restenosis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00212/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00212/full

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