Evaluation of Signaling Pathways Involved in γ-Globin Gene Induction Using Fetal Hemoglobin Inducer Drugs
Potent induction of fetal hemoglobin (HbF) production results in alleviating the complications of β-thalassemia and sickle cell disease (SCD). HbF inducer agents can trigger several molecular signaling pathways critical for erythropoiesis. Janus kinase/Signal transducer and activator of transcripti...
Main Authors: | Fakher Rahim, Hossein Allahmoradi, Fatemeh Salari, Mohammad Shahjahani, Ali Dehghani Fard, Seyed Ahmad Hosseini, Hadi Mousakhani |
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Format: | Article |
Language: | English |
Published: |
Tehran University of Medical Sciences
2013-09-01
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Series: | International Journal of Hematology-Oncology and Stem Cell Research |
Subjects: | |
Online Access: | https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/445 |
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