Disentangling the roles of maternal and paternal age on birth prevalence of Down syndrome and other chromosomal disorders using a Bayesian modeling approach
Abstract Background Multiple neonatal and pediatric disorders have been linked to older paternal ages. Combining these findings with the evidence that many men are having children at much later ages generates considerable public health concern. The risk of paternal age has been difficult to estimate...
Main Author: | James A. Thompson |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2019-04-01
|
Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12874-019-0720-1 |
Similar Items
-
Maternal uniparental isodisomy for chromosome 6 discovered by paternity testing: a case report
by: Elizabeth R. Kerr, et al.
Published: (2018-12-01) -
The risks of advancing parental age on neonatal morbidity and mortality are U- or J-shaped for both maternal and paternal ages
by: James A. Thompson
Published: (2020-09-01) -
Related factors associated with the birth of children with Down syndrome
by: Farhud DD, et al.
Published: (2012-08-01) -
Advancing paternal age does not affect in-vitro fertilization (IVF) outcomes in a Saudi population
by: Samaher Saud Alfaraj, et al.
Published: (2015-09-01) -
Telomere Length in Metaphase Chromosomes of Human Triploid Zygotes
by: Anna A. Pendina, et al.
Published: (2021-05-01)