Cysteine Proteases from V. cundinamarcensis (C. candamarcensis) Inhibit Melanoma Metastasis and Modulate Expression of Proteins Related to Proliferation, Migration and Differentiation

Cysteine Proteases from V. cundinamarcensis (C. candamarcensis) Inhibit Melanoma Metastasis and Modulate Expression of Proteins Related to Proliferation, Migration and Differentiation

Previous studies showed that P1G10, a proteolytic fraction from Vasconcellea cundinamarcensis latex, reduced the tumor mass in animals bearing melanoma, increased in vitro DNA fragmentation and decreased cell adhesion. Here, we present some molecular and cellular events related to the antimetastatic...

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Bibliographic Details
Main Authors: Fernanda O. Lemos, Dalton Dittz, Verlane G. Santos, Simone F. Pires, Hélida M. de Andrade, Carlos E. Salas, Miriam T. P. Lopes
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
cysteine proteases
antimetastatic
melanoma
cell migration
melanogenesis
cell differentiation
Online Access:http://www.mdpi.com/1422-0067/19/10/2846

Internet

http://www.mdpi.com/1422-0067/19/10/2846

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