Arsenic trioxide, a potent inhibitor of NF-κB, abrogates allergen-induced airway hyperresponsiveness and inflammation

<p>Abstract</p> <p>Background</p> <p>Overactivation of nuclear factor κB (NF-κB) orchestrates airway eosinophilia, but does not dampen airway hyperresponsiveness in asthma. NF-κB repression by arsenic trioxide (As<sub>2</sub>O<sub>3</sub>) contri...

Full description

Bibliographic Details
Main Authors: Xie Wei-Ping, Cui Xue-Fan, Zhu Yi, Zhou Lin-Fu, Hu Ai-Hua, Yin Kai-Sheng
Format: Article
Language:English
Published: BMC 2006-12-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/7/1/146