Arsenic trioxide, a potent inhibitor of NF-κB, abrogates allergen-induced airway hyperresponsiveness and inflammation
<p>Abstract</p> <p>Background</p> <p>Overactivation of nuclear factor κB (NF-κB) orchestrates airway eosinophilia, but does not dampen airway hyperresponsiveness in asthma. NF-κB repression by arsenic trioxide (As<sub>2</sub>O<sub>3</sub>) contri...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-12-01
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Series: | Respiratory Research |
Online Access: | http://respiratory-research.com/content/7/1/146 |