Melatonin Modifies Histone Acetylation during In Vitro Maturation of Mouse Oocytes

Melatonin Modifies Histone Acetylation during In Vitro Maturation of Mouse Oocytes

Objective We evaluated the effect of melatonin, as a potent antioxidant agent, on glutathione (GSH) and reactive oxygen species (ROS) levels, as well as histone H3 lysine 9 (H3K9), and H4 lysine 12 (H4K12) acetylation when added to oocytes culture medium. Materials and Methods In this experimen...

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Main Authors: Somayeh Keshavarzi, Mohammad Salehi, Fattaneh Farifteh-Nobijari, Taher Hosseini, Sara Hosseini, Alaleh Ghazifard, Marefat Ghaffari Novin, Vahid Fallah-Omrani, Mohsen Nourozian, Ahmad Hosseini
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2018-04-01
Series:Cell Journal
Subjects:
Glutathione
In Vitro Oocyte Maturation
Melatonin
Reactive Oxygen Species
Online Access:http://celljournal.org/journal/article/19692/download

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