Role of Genetic Variations in the Hepatic Handling of Drugs

Role of Genetic Variations in the Hepatic Handling of Drugs

The liver plays a pivotal role in drug handling due to its contribution to the processes of detoxification (phases 0 to 3). In addition, the liver is also an essential organ for the mechanism of action of many families of drugs, such as cholesterol-lowering, antidiabetic, antiviral, anticoagulant, a...

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Bibliographic Details
Main Authors: Jose J. G. Marin, Maria A. Serrano, Maria J. Monte, Anabel Sanchez-Martin, Alvaro G. Temprano, Oscar Briz, Marta R. Romero
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
detoxification
haplotype
isoform
metabolism
mutation
pharmacogenomics
Online Access:https://www.mdpi.com/1422-0067/21/8/2884

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