Life Cycle Stage-Specific Accessibility of <named-content content-type="genus-species">Leishmania donovani</named-content> Chromatin at Transcription Start Regions

Life Cycle Stage-Specific Accessibility of <named-content content-type="genus-species">Leishmania donovani</named-content> Chromatin at Transcription Start Regions

ABSTRACT Leishmania donovani is a parasitic protist that causes the lethal Kala-azar fever in India and East Africa. Gene expression in Leishmania is regulated by gene copy number variation and inducible translation while RNA synthesis initiates at a small number of sites per chromosome and proceeds...

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Bibliographic Details
Main Authors: Janne Grünebast, Stephan Lorenzen, Julia Zummack, Joachim Clos
Format: Article
Language:English
Published: American Society for Microbiology 2021-08-01
Series:mSystems
Subjects:
nucleosomes
micrococcal nuclease
radicicol
HSP90
strand switch regions
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00628-21

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