ACTN1 supports tumor growth by inhibiting Hippo signaling in hepatocellular carcinoma

Abstract Background Alpha actinins (ACTNs) are major cytoskeletal proteins and exhibit many non-muscle functions. Emerging evidence have uncovered the regulatory role of ACTNs in tumorigenesis, however, the expression pattern, biological functions, and underlying mechanism of ACTN1 in hepatocellular...

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Bibliographic Details
Main Authors: Qian Chen, Xiao-Wei Zhou, Ai-Jun Zhang, Kang He
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13046-020-01821-6