Trichinella spiralis paramyosin activates mouse bone marrow-derived dendritic cells and induces regulatory T cells

Abstract Background Dendritic cells (DCs) are antigen-presenting cells that regulate T cell responses for many infectious diseases. The tissue-dwelling nematode Trichinella spiralis expresses paramyosin (TsPmy) not only as a structural protein but also as an immunomodulator to alleviate complement a...

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Bibliographic Details
Main Authors: Kai Guo, Ximeng Sun, Yuan Gu, Zixia Wang, Jingjing Huang, Xinping Zhu
Format: Article
Language:English
Published: BMC 2016-11-01
Series:Parasites & Vectors
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13071-016-1857-y