High-Throughput Sequencing-Based Analysis of T Cell Repertoire in Lupus Nephritis

High-Throughput Sequencing-Based Analysis of T Cell Repertoire in Lupus Nephritis

T cell receptor (TCR)-mediated immune functions are closely related to autoimmune diseases, such as systemic lupus erythematosus (SLE). However, technical challenges used to limit the accurate profiling of TCR diversity in SLE and the characteristics of SLE patients remain largely unknown. In this s...

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Bibliographic Details
Main Authors: Xiaolan Ye, Zhe Wang, Qiang Ye, Jing Zhang, Ping Huang, Jingying Song, Yiwen Li, Hongjuan Zhang, Feifeng Song, Zixue Xuan, Kejian Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
T cell receptor
lupus nephritis
systemic lupus erythematosus
immune repertoire
next-generation sequencing
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01618/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01618/full

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