Large-scale bioactivity analysis of the small-molecule assayed proteome.
This study presents an analysis of the small molecule bioactivity profiles across large quantities of diverse protein families represented in PubChem BioAssay. We compared the bioactivity profiles of FDA approved drugs to non-FDA approved compounds, and report several distinct patterns characteristi...
Main Authors: | Tyler William H Backman, Daniel S Evans, Thomas Girke |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0171413 |
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