Global Transcriptomic Analysis of Zebrafish Glucagon Receptor Mutant Reveals Its Regulated Metabolic Network

Global Transcriptomic Analysis of Zebrafish Glucagon Receptor Mutant Reveals Its Regulated Metabolic Network

The glucagon receptor (GCGR) is a G-protein-coupled receptor (GPCR) that mediates the activity of glucagon. Disruption of GCGR results in many metabolic alterations, including increased glucose tolerance, decreased adiposity, hypoglycemia, and pancreatic α-cell hyperplasia. To better unders...

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Bibliographic Details
Main Authors: Qi Kang, Mengyi Hu, Jianxin Jia, Xuanxuan Bai, Chengdong Liu, Zhiqiang Wu, Wenbiao Chen, Mingyu Li
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
glucagon receptor
zebrafish
rna sequencing
metabolic network
diabetes
Online Access:https://www.mdpi.com/1422-0067/21/3/724

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