Differences in Extracellular Vesicle Protein Cargo Are Dependent on Head and Neck Squamous Cell Carcinoma Cell of Origin and Human Papillomavirus Status

Differences in Extracellular Vesicle Protein Cargo Are Dependent on Head and Neck Squamous Cell Carcinoma Cell of Origin and Human Papillomavirus Status

To identify potential extracellular vesicle (EV) biomarkers in head and neck squamous cell carcinoma (HNSCC), we evaluated EV protein cargo and whole cell lysates (WCL) from HPV-positive and -negative HNSCC cell lines, as well as normal oral keratinocytes and HPV16-transformed cells. EVs were isolat...

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Bibliographic Details
Main Authors: Christine Goudsmit, Felipe da Veiga Leprevost, Venkatesha Basrur, Lila Peters, Alexey Nesvizhskii, Heather Walline
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
HPV
head and neck squamous cell carcinoma
extracellular vesicle
proteomic
Online Access:https://www.mdpi.com/2072-6694/13/15/3714

Internet

https://www.mdpi.com/2072-6694/13/15/3714

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