Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents

Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents

Cross-coupling reactions typically are carried out under dilute conditions of ethereal solvents. Here, the authors report a method for palladium catalysed cross-coupling of organolithium reagents that avoids the use of any added solvent with reaction times of only minutes.

Bibliographic Details
Main Authors: Erik B. Pinxterhuis, Massimo Giannerini, Valentín Hornillos, Ben L. Feringa
Format: Article
Language:English
Published: Nature Publishing Group 2016-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11698
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spelling doaj-5c846e9746fc48718a23e4f9ead6ec8d2021-05-11T10:39:37ZengNature Publishing GroupNature Communications2041-17232016-06-01711710.1038/ncomms11698Fast, greener and scalable direct coupling of organolithium compounds with no additional solventsErik B. Pinxterhuis0Massimo Giannerini1Valentín Hornillos2Ben L. Feringa3Faculty of Mathematics and Natural Sciences, Stratingh Institute for Chemistry, University of GroningenFaculty of Mathematics and Natural Sciences, Stratingh Institute for Chemistry, University of GroningenFaculty of Mathematics and Natural Sciences, Stratingh Institute for Chemistry, University of GroningenFaculty of Mathematics and Natural Sciences, Stratingh Institute for Chemistry, University of GroningenCross-coupling reactions typically are carried out under dilute conditions of ethereal solvents. Here, the authors report a method for palladium catalysed cross-coupling of organolithium reagents that avoids the use of any added solvent with reaction times of only minutes.https://doi.org/10.1038/ncomms11698
collection DOAJ
language English
format Article
sources DOAJ
author Erik B. Pinxterhuis
Massimo Giannerini
Valentín Hornillos
Ben L. Feringa
spellingShingle Erik B. Pinxterhuis
Massimo Giannerini
Valentín Hornillos
Ben L. Feringa
Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
Nature Communications
author_facet Erik B. Pinxterhuis
Massimo Giannerini
Valentín Hornillos
Ben L. Feringa
author_sort Erik B. Pinxterhuis
title Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
title_short Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
title_full Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
title_fullStr Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
title_full_unstemmed Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
title_sort fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2016-06-01
description Cross-coupling reactions typically are carried out under dilute conditions of ethereal solvents. Here, the authors report a method for palladium catalysed cross-coupling of organolithium reagents that avoids the use of any added solvent with reaction times of only minutes.
url https://doi.org/10.1038/ncomms11698
work_keys_str_mv AT erikbpinxterhuis fastgreenerandscalabledirectcouplingoforganolithiumcompoundswithnoadditionalsolvents
AT massimogiannerini fastgreenerandscalabledirectcouplingoforganolithiumcompoundswithnoadditionalsolvents
AT valentinhornillos fastgreenerandscalabledirectcouplingoforganolithiumcompoundswithnoadditionalsolvents
AT benlferinga fastgreenerandscalabledirectcouplingoforganolithiumcompoundswithnoadditionalsolvents
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