Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients with Hereditary Medullary Thyroid Carcinoma

Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients with Hereditary Medullary Thyroid Carcinoma

Medullary thyroid carcinoma occurs in both sporadic (75%) and hereditary (25%) forms. The missense mutations of RET proto-oncogene in MTC development have been well demonstrated. To investigate the spectrum of predominant RET germline mutations in exons 10, 11, and 16 in hereditary MTC in Iranian po...

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Bibliographic Details
Main Authors: Mehdi Hedayati, Marjan Zarif Yeganeh, Sara Sheikhol Eslami, Shekoofe Rezghi Barez, Laleh Hoghooghi Rad, Fereidoun Azizi
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Thyroid Research
Online Access:http://dx.doi.org/10.4061/2011/264248

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