The management of orthostatic hypotension in Parkinson's disease

• Main Authors: Alvaro eSanchez-Ferro, Julián eBenito-León, Juan Carlos eGomez-Esteban
• Format: Article
• Language: English
• Published: Frontiers Media S.A. 2013-06-01
• Series: Frontiers in Neurology
• Subjects: Dopamine Agonists; L-Dopa; Parkinson’s disease; Treatment; orthostatic hypotension; continuous dopaminergic stimulation
• Online Access: http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00064/full

Orthostatic hypotension is a common and disabling symptom affecting Parkinson’s disease (PD) patients. We present the effect of the different therapies commonly used to manage Parkinson’s disease on this clinical manifestation. For this purpose, we describe the relationship between orthostatic hypotension and the current treatments employed in PD, such as L-Dopa, dopaminergic agonists, and continuous dopaminergic stimulation therapies. Additionally, we review the therapeutic measures that could be used to ameliorate orthostatic hypotension. There are different approaches to deal with this manifestation, including pharmacological and non-pharmacological treatments, although none of them is specifically aimed for treating orthostatic hypotension in PD.